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Article

Polymorphisms in the 5'-upstream region of the PKCbeta gene in Japanese patients with Type 2 diabetes.

Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 2004

Ikeda Y, Suehiro T, Osaki F, Tsuzura S, Kumon Y, Hashimoto K

Abstract excerpt

AIMS: Protein kinase C (PKC), a serine/threonine kinase, is known to be activated in various tissues under hyperglycaemic conditions. Notably, PKCbeta, a member of the conventional PKC group, is the predominant isoform detected in vascular tissues and could be involved in the development of diabetic vascular complications. In the present study, we investigated genetic variations in the 5'-upstream region of the...

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Identifiers

PMID: 15384959
DOI: 10.1111/j.1464-5491.2004.01304.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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