Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinoma

21 Jun 2023

Abstract excerpt

BACKGROUND: PRKCG encodes PKC γ, which is categorized under the classical protein kinase C family. No studies have specifically established the relationship between PRKCG nsSNPs with structural and functional variations in PKC γ in the context of hepatocellular carcinoma (HCC). The present study aims to uncover this link through in-silico and experimental studies. METHODS: The 3D structure of PKC γ was predicted....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Protein Kinase Regulation and GTPase Signaling
Share to Protein Tyrosine Phosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37344815
DOI: 10.1186/s12935-023-02965-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinomaPMID 37344815Read ↗

Computational insights into PKCθ non-synonymous SNPs: from structural changes to functional implications.Semantic proximity Read ↗

Influence of PRKCE non-synonymous variants on protein dynamics and functionality.Semantic proximity Read ↗

Comprehensive computational analysis of PKCδ non-synonymous variants identifies rs1703863535 as a potential breast cancer biomarker.Semantic proximity Read ↗

Investigating pathogenic SNP of PKCι in HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

A recurrent point mutation in PRKCA is a hallmark of chordoid gliomasSemantic proximity Read ↗

Investigation of UTR Variants by Computational Approaches Reveal Their Functional Significance in PRKCI Gene Regulation.Semantic proximity Read ↗

Genetic polymorphism in untranslated regions of PRKCZ influences mRNA structure, stability and binding sites.Semantic proximity Read ↗

Impact of deleterious missense PRKCI variants on structural and functional dynamics of protein.Semantic proximity Read ↗

Molecular genetics and structural genomics of the human protein kinase C gene module.Semantic proximity Read ↗

Genetic analysis of key players in PI3K signaling cascade of colorectal carcinoma.Semantic proximity Read ↗

Pan-Cancer Study on Protein Kinase C Family as a Potential Biomarker for the Tumors Immune Landscape and the Response to ImmunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.