Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of SNPs in protein kinase C zeta gene on gene expression in the reporter gene detection system.

World journal of gastroenterology - 15 Aug 2004

Liu Zhuo, Sun Hong-Xia, Zhang Yong-Wei, Li Yun-Feng, Zuo Jin, Meng Yan, Fang Fu-De

Abstract excerpt

AIM: To investigated the effects of the SNPs (rs411021, rs436045, rs427811, rs385039 and rs809912) on gene expression and further identify the susceptibility genes of type 2 diabetes. METHODS: Ten allele fragments (49 bp each) were synthesized according to the 5 SNPs mentioned above. These fragments were cloned into luciferase reporter gene vector and then transfected into HepG2 cells. The activity of the...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Gene Expression Regulation, Enzymologic
Share to Genes, Reporter
Share to Introns
Share to Luciferases
Share to Protein Kinase C
Share to Transcription, Genetic
Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 15285019
DOI: 10.3748/wjg.v10.i16.2357
PMCID: PMC4576288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of SNPs in protein kinase C zeta gene on gene expression in the reporter gene detection system.PMID 15285019Read ↗

Protein kinase C/zeta (PRKCZ) gene is associated with type 2 diabetes in Han population of North China and analysis of its haplotypes.Semantic proximity Read ↗

[Functional analysis of the single nucleotide polymorphisms in the PRKCZ gene].Semantic proximity Read ↗

Genetic variants in protein kinase C zeta gene and type 2 diabetes risk: a case-control study of a Chinese Han population.Semantic proximity Read ↗

Polymorphisms in the 5'-upstream region of the PKCbeta gene in Japanese patients with Type 2 diabetes.Semantic proximity Read ↗

Identification and functional analysis of variant haplotypes in the 5'-flanking region of protein phosphatase 2A-Bδ gene.Semantic proximity Read ↗

Variation in the PTEN-induced putative kinase 1 gene associated with the increase risk of type 2 diabetes in northern Chinese.Semantic proximity Read ↗

Polymorphisms in the human glutathione transferase Kappa (GSTK1) promoter alter gene expression.Semantic proximity Read ↗

Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinomaSemantic proximity Read ↗

Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

Association between peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene polymorphisms and type 2 diabetes in southern Chinese population: role of altered interaction with myocyte enhancer factor 2C.Semantic proximity Read ↗

Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus.Semantic proximity Read ↗

Investigating pathogenic SNP of PKCι in HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.