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Article

TLR4 Asp299Gly and Thr399Ile polymorphisms are very rare in the Chinese population.

Journal of endotoxin research - 1 Jan 2004

Hang Jingqing, Zhou Wei, Zhang Hongxi, Sun Bixiong, Dai Helian, Su Li, Christiani David C

Abstract excerpt

Endotoxin is an important component of bio-aerosols that contribute to airway inflammation and airflow obstruction. Toll-like receptor 4 (TLR4) mediates the host response to bacterial lipopolysaccharide (LPS), and the Asp299Gly and Thr399Ile polymorphisms have been associated with the development of respiratory diseases. We hypothesized that TLR4 polymorphisms may be associated with a decline of lung function in...

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Source

Identifiers

PMID: 15373967
DOI: 10.1179/096805104225005841

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TLR4 Asp299Gly and Thr399Ile polymorphisms are very rare in the Chinese population.PMID 15373967Read ↗

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Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness.Semantic proximity Read ↗

The Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms influence the late inflammatory response in human endotoxemia.Semantic proximity Read ↗

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