Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TLR4 gene variants modify endotoxin effects on asthma.

The Journal of allergy and clinical immunology - 1 Aug 2003

Werner Monika, Topp Rebekka, Wimmer Katrin, Richter Kai, Bischof Wolfgang, Wjst Matthias, Heinrich Joachim

Abstract excerpt

BACKGROUND: Environmental exposure to endotoxin might have a crucial role in immune maturation and development of asthma. OBJECTIVE: The aim of this study was to investigate whether the effect of endotoxin concentration in settled house dust on asthma is modified by the presence of variation in the TLR4 gene. METHODS: We performed a cross-sectional study within the German follow-up of the European Community...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Cross-Sectional Studies
Share to Dust

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endotoxins

Share to Odds Ratio

Share to Osmolar Concentration

Share to Respiratory Sounds

Share to Risk Assessment

Source

Identifiers

PMID: 12897738
DOI: 10.1067/mai.2003.1648

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TLR4 gene variants modify endotoxin effects on asthma.PMID 12897738Read ↗

Endotoxin exposure, CD14 and wheeze among farmers: a gene--environment interaction.Semantic proximity Read ↗

The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma.Semantic proximity Read ↗

Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment.Semantic proximity Read ↗

The effect of CD14 and TLR4 gene polymorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study.Semantic proximity Read ↗

Polymorphisms of endotoxin pathway and endotoxin exposure: in vitro IgE synthesis and replication in a birth cohort.Semantic proximity Read ↗

Genetic variants in endotoxin signalling pathway, domestic endotoxin exposure and asthma exacerbations.Semantic proximity Read ↗

The role of lipopolysaccharide in the development of atopy in humans.Semantic proximity Read ↗

Association of polymorphisms of toll-like receptor 4 with a reduced prevalence of hay fever and atopy.Semantic proximity Read ↗

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans.Semantic proximity Read ↗

TLR4 and LPS hyporesponsiveness in humans.Semantic proximity Read ↗

The role of TLR4 in endotoxin responsiveness in humans.Semantic proximity Read ↗

Mice Expressing Cosegregating Single Nucleotide Polymorphisms (D298G and N397I) in TLR4 Have Enhanced Responses to House Dust Mite Allergen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.