Article
Haplotype-tagging RANTES gene variants influence response to antiviral therapy in chronic hepatitis C.
Hepatology (Baltimore, Md.) - 1 Aug 2004
Wasmuth Hermann E, Werth Alexa, Mueller Tobias, Berg Thomas, Dietrich Christoph G, Geier Andreas, Gartung Carsten, Lorenzen Johann, Matern Siegfried, Lammert Frank
Abstract excerpt
The response to antiviral therapy for chronic hepatitis C virus (HCV) is complex and is determined by both environmental and genetic factors. Recently, interacting gene polymorphisms of the chemokine RANTES have been shown to affect HIV disease progression. Our aim was to assess if these RANTES variants are associated with response to anti-HCV therapy. Three linked RANTES single nucleotide polymorphisms (403 G/A,...
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