Article
Distribution and effects of polymorphic RANTES gene alleles in HIV/HCV coinfection -- a prospective cross-sectional study.
World journal of gastroenterology - 28 Dec 2005
Ahlenstiel Golo, Iwan Agathe, Nattermann Jacob, Bueren Karin, Rockstroh Jurgen K, Brackmann Hans H, Kupfer Bernd, Landt Olfert, Peled Amnon, Sauerbruch Tilman, Spengler Ulrich, Woitas Rainer P
Abstract excerpt
AIM: Chemokines and their receptors are crucial for immune responses in HCV and HIV infection. RANTES gene polymorphisms lead to altered gene expression and influence the natural course of HIV infection. Therefore, these mutations may also affect the course of HIV/HCV coinfection. METHODS: We determined allele frequencies of RANTES-403 (G --> A), RANTES-28 (C --> G) and RANTES-IN1.1 (T --> C) polymorphisms using...
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