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Article

Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.

The Journal of general virology - 1 Jan 2013

Nakano Rikita, Maekawa Toshiro, Abe Hiromi, Hayashida Yasufumi, Ochi Hidenori, Tsunoda Tatsuhiko, Kumada Hiromitsu, Kamatani Naoyuki, Nakamura Yusuke, Chayama Kazuaki

Abstract excerpt

New anti-hepatitis C virus (HCV) therapeutics developed recently are more effective and lead to improvements in sustained viral response. However, interferon (IFN) monotherapy is still used to a limited extent for fear of adverse effects. This study investigated host genetic factors affecting the IFN response in patients with chronic hepatitis C (CHC). Using a two-step design, a large-scale association screening...

Read the complete abstract on PubMed

Topics

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Share to Antiviral Agents
Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferons

Share to N-Acetylgalactosaminyltransferases

Share to Polypeptide N-acetylgalactosaminyltransferase

Share to Ribavirin

Share to Virus Replication

Source

Identifiers

PMID: 23034592
DOI: 10.1099/vir.0.044396-0

Genes

GALNT8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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