Article
RANTES gene polymorphisms (-403G>A and -28C>G) associated with hepatitis B virus infection in a Saudi population.
Genetics and molecular research : GMR - 10 Apr 2012
Al-Qahtani A, Alarifi S, Al-Okail M, Hussain Z, Abdo A, Sanai F, Al-Anazi M, Khalaf N, Al-Humaidan H, Al-Ahdal M, Almajhdi F N
Abstract excerpt
Besides the host immune response, genetic and environmental factors play crucial roles in the manifestation of hepatitis B virus (HBV) infection. "Regulated on activation normal T-cell expressed and secreted" factor (RANTES) plays a vital role in CD4(+), CD8(+) T-lymphocyte and dendritic cell activation and proliferation in inflammation. Single nucleotide polymorphisms (SNPs) in the RANTES gene are...
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