Article
A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Journal of hepatology - 1 Apr 2011
Fujimoto Yoshifumi, Ochi Hidenori, Maekawa Toshiro, Abe Hiromi, Hayes C Nelson, Kumada Hiromitsu, Nakamura Yusuke, Chayama Kazuaki
Abstract excerpt
BACKGROUND & AIMS: Cdc42 is a Rho family GTPase protein and was recently implicated in mediating hepatitis C virus (HCV) infectivity. This study examines the association between Cdc42-related gene and interferon (IFN) therapy in HCV patients. METHODS: We analyzed the associations between the outc...
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