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Article

A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.

Journal of hepatology - 1 Apr 2011

Fujimoto Yoshifumi, Ochi Hidenori, Maekawa Toshiro, Abe Hiromi, Hayes C Nelson, Kumada Hiromitsu, Nakamura Yusuke, Chayama Kazuaki

Abstract excerpt

BACKGROUND & AIMS: Cdc42 is a Rho family GTPase protein and was recently implicated in mediating hepatitis C virus (HCV) infectivity. This study examines the association between Cdc42-related gene and interferon (IFN) therapy in HCV patients. METHODS: We analyzed the associations between the outcome of IFN therapy and 17 tagging single nucleotide polymorphisms (SNPs) within two genes involved in Cdc42 signaling...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21129804
DOI: 10.1016/j.jhep.2010.07.021

Genes

CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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