Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

doi:10.1136/gut.2009.202267

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Article

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

Gut - 1 Aug 2010

Nalpas Bertrand, Lavialle-Meziani Roubila, Plancoulaine Sabine, Jouanguy Emmanuelle, Nalpas Antoine, Munteanu Mona, Charlotte Frederic, Ranque Brigitte, Patin Etienne, Heath Simon, Fontaine Hélène, Vallet-Pichard Anaïs, Pontoire Dominique, Bourlière Marc, Casanova Jean-Laurent, Lathrop Mark, Bréchot Christian, Poynard Thierry, Matsuda Fumihiko, Pol Stanislas, Abel Laurent

Abstract excerpt

BACKGROUND: Only a minority of patients with chronic hepatitis C virus (HCV) infection develops severe liver fibrosis, a process that may be controlled by human genetic factors. OBJECTIVE: To investigate the role of 384 single nucleotide polymorphisms (SNPs) located in 36 candidate genes related to the fibrogenesis/fibrolysis process. METHODS: Patients with chronic HCV infection were gathered from two French...

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Identifiers

PMID: 20587546
DOI: 10.1136/gut.2009.202267

Genes

IFNGR2

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