Article
Gene-gene and gene-environment interactions in interferon therapy for chronic hepatitis C.
Pharmacogenomics - 1 Oct 2007
Lin Eugene, Hwang Yuchi, Chen Ellson Y
Abstract excerpt
INTRODUCTION: In studies of pharmacogenomics, it is essential to address gene-gene and gene-environment interactions to describe complex traits involving pharmacokinetic and pharmacodynamic mechanisms. In this work, our goal is to detect gene-gene and gene-environment interactions resulting from an analysis of chronic hepatitis C patients' clinical factors including SNPs, viral genotype, viral load, age and...
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