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Article

Monovalent ion-mediated folding of the Tetrahymena thermophila ribozyme.

Journal of molecular biology - 1 Oct 2004

Shcherbakova Inna, Gupta Sayan, Chance Mark R, Brenowitz Michael

Abstract excerpt

The time-course of monovalent cation-induced folding of the L-21 Sca1 Tetrahymena thermophila ribozyme and a selected mutant was quantitatively followed using synchrotron X-ray (.OH) footprinting. Initiating folding by increasing the concentration of either Na+ or K+ to 1.5M from an initial condition of approximately 0.008 M Na+ at 42 degrees C resulted in the complete formation of tertiary contacts within the...

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Source

Identifiers

PMID: 15364572
DOI: 10.1016/j.jmb.2004.07.092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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