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Article

The ion-induced folding of the hammerhead ribozyme: core sequence changes that perturb folding into the active conformation.

RNA (New York, N.Y.) - 1 Aug 1996

Bassi G S, Murchie A I, Lilley D M

Abstract excerpt

The hammerhead ribozyme undergoes an ion-dependent folding process into the active conformation. We find that the folding can be blocked at specific stages by changes of sequence or functionality within the core. In the the absence of added metal ions, the global structure of the hammerhead is ex...

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Identifiers

PMID: 8752086
PMCID: PMC1369413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8752086-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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