Article
Associations of the -344 T>C and the 3097 G>A polymorphisms of CYP11B2 gene with hypertension, type 2 diabetes, and metabolic syndrome in a French population.
American journal of hypertension - 1 Jun 2010
Bellili Naïma Muñoz, Foucan Lydia, Fumeron Frédéric, Mohammedi Kamel, Travert Florence, Roussel Ronan, Balkau Beverley, Tichet Jean, Marre Michel
Abstract excerpt
BACKGROUND: Aldosterone can affect both blood pressure (BP) and glucose metabolism. We assessed the association of two polymorphisms -344 T>C and the 3097 G>A in the aldosterone synthase gene (CYP11B2) with prevalent and incident hypertension (HT), type 2 diabetes (T2D), and the metabolic syndrome (MetS). METHODS: We studied the 5,212 participants to D.E.S.I.R. (Data from Epidemiologic Study on the Insulin...
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