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Aldosterone Synthase CYP11B2 Gene Promoter Polymorphism in a Turkish Population With Chronic Kidney Disease.

Iranian journal of kidney diseases - 1 May 2015

Yilmaz Meral, Sari Ismail, Bagci Binnur, Gumus Erkan, Ozdemir Ozturk

Abstract excerpt

INTRODUCTION: It has been shown that gene polymorphisms influence the development and progression of chronic kidney disease (CKD). Many studies have indicated that aldosterone synthase CYP11B2 gene polymorphism (-344C>T) influences the aldosterone level, urinary aldosterone excretion, blood pressure, and left ventricular size and mass. We aimed to investigate whether there is an effect of CYP11B2 -344 C>T...

Topics

Adult
Aged
Case-Control Studies
Cytochrome P-450 CYP11B2
Diabetic Nephropathies
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Promoter Regions, Genetic

Renal Insufficiency, Chronic

Turkey

Source

Identifiers

PMID: 25957425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Aldosterone Synthase CYP11B2 Gene Promoter Polymorphism in a Turkish Population With Chronic Kidney Disease.PMID 25957425Read ↗

The cytochrome 11B2 aldosterone synthase gene CYP11B2 (RS1799998) polymorphism associates with chronic kidney disease in hypertensive patientsSemantic proximity Read ↗

Association of aldosterone synthase (CYP11B2) -344 T/C polymorphism with diabetic nephropathy: A meta-analysis.Semantic proximity Read ↗

The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.Semantic proximity Read ↗

Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients.Semantic proximity Read ↗

Associations of the -344 T>C and the 3097 G>A polymorphisms of CYP11B2 gene with hypertension, type 2 diabetes, and metabolic syndrome in a French population.Semantic proximity Read ↗

Association of aldosterone synthase CYP11B2 (-344C/T) gene polymorphism with essential hypertension and left ventricular hypertrophy in the Egyptian populationSemantic proximity Read ↗

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-344C/T Variant in the promoter of the aldosterone synthase gene (CYP11B2) is associated with metabolic syndrome in men.Semantic proximity Read ↗

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