Article
Characterization of recessive (mediator-) revertants from NIH 3T3 cells transformed with a c-H-ras oncogene.
The Journal of biological chemistry - 25 Feb 1991
Yamada H, Omata-Yamada T, Lengyel P
Abstract excerpt
We have reported earlier the isolation of two recessive, serum- and anchorage-dependent revertants from an NIH 3T3 line which had been transformed with multiple copies of a c-H-ras oncogene. In both revertants the oncogene was fully expressed and fusion of either revertant with normal (untransformed) cells or of the two revertants with one another resulted in transformed progeny. These, and other data indicate...
Topics
- Cell Line, Transformed
- Electrophoresis, Polyacrylamide Gel
- Genes, ras
- Monosaccharide Transport Proteins
- Mutation
- Phosphorylation
- Protein Kinases
- RNA, Messenger
- Tyrosine