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Article

The dynamics of X‐inactivation skewing as women age

8 Sept 2004

Abstract excerpt

Non-random X-chromosome inactivation (XCI) has been associated with X-linked diseases, neoplastic diseases, recurrent pregnancy loss, and trisomy risk. It also occurs more commonly in older female populations. To understand the etiology of non-random XCI and utilize this assay appropriately in clinical research and practice, the age-related alteration in XCI patterns in normal females needs to be clearly defined....

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 15355435
DOI: 10.1111/j.1399-0004.2004.00310.x

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The dynamics of X‐inactivation skewing as women agePMID 15355435Read ↗

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