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Article

Skewed X inactivation in healthy individuals and in different diseases

1 Apr 2006

Abstract excerpt

UNLABELLED: In female mammalian cells, one of the two X chromosomes is inactivated in early embryonic life. Females are mosaics for two cell populations, one with the maternal and one with the paternal X as the active chromosome. Skewed X inactivation is arbitrarily defined, often as a pattern where 80% or more of the cells show a preferential inactivation of one X chromosome. Inactivation is presumed to be...

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Identifiers

PMID: 16720461
DOI: 10.1080/08035320600618783

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Source receipt: pubmed, retrieved 7 Sept 2026.

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