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Article

Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior.

The Journal of biological chemistry - 5 Nov 2004

Mi Zhiyong, Guo Hongtao, Wai Philip Y, Gao Chengjiang, Wei Junping, Kuo Paul C

Abstract excerpt

Cancer progression depends on an accumulation of metastasis-supporting cell signaling molecules, which target signal transduction pathways and, ultimately, gene expression. One such molecule, osteopontin (OPN), represents a key molecular signaling event in tumor progression and metastasis. However, the transcriptional regulatory mechanisms that underlie OPN expression in the setting of breast cancer have not been...

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PMID: 15347645
DOI: 10.1074/jbc.M407952200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior.PMID 15347645Read ↗

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