Article
An osteopontin splice variant induces anchorage independence in human breast cancer cells.
Oncogene - 6 Apr 2006
He B, Mirza M, Weber G F
Abstract excerpt
In malignant tumors, metastasis genes are typically deregulated by aberrant expression or splicing. Osteopontin is expressed at high levels by various cancers and contributes importantly to their invasive potential. In contrast, osteopontin derived from host cells induces cellular immunity and co...
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