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Article

Role of osteopontin in tumour progression

27 Apr 2004

Abstract excerpt

Since its first identification as a transformation-associated protein, osteopontin (OPN) has been recognised as important in the processes of tumorigenicity and metastasis. Here, we review the evidence that OPN might be considered as a candidate prognostic marker in human cancer. In animal systems, evidence from cell injection experiments and genetically manipulated mice suggest an important but complex role for...

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PMID: 15138464
DOI: 10.1038/sj.bjc.6601839

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