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Article

STAT3 is dispensable for maintenance of self-renewal in nonhuman primate embryonic stem cells.

Stem cells (Dayton, Ohio) - 1 Jan 2004

Sumi Tomoyuki, Fujimoto Yasuko, Nakatsuji Norio, Suemori Hirofumi

Abstract excerpt

The leukemia inhibitory factor (LIF)/glycoprotein 130 (gp130)/signal transducer and activator of transcription 3 (STAT3) pathway plays an essential role in the maintenance of self-renewal and pluripotency in mouse embryonic stem (ES) cells. However, in primate ES cells, including those from humans and monkeys, LIF alone is not sufficient to maintain self-renewal. The precise role of the LIF/gp130/STAT3 pathway...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15342949
DOI: 10.1634/stemcells.22-5-861

Genes

LIF
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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