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The Regulation of Self-Renewal in Human Embryonic Stem Cells

1 Oct 2006

Abstract excerpt

Human embryonic stem (hES) cells have the ability to self-renew while maintaining their pluripotency. The ability of stem cells to self-renew expansively is essential in both development and maintenance of adult tissues. ES cell lines were first generated from mouse blastocysts, these lines provided much needed information regarding ES cell propagation, growth factor dependence, and marker expression. However,...

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PMID: 17105408
DOI: 10.1089/scd.2006.15.729

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