Article
Humoral and cell surface interactions during gamma-irradiation leukemogenesis in vitro.
Experimental hematology - 1 Jan 1992
Greenberger J, Leif J, Crawford D, Anklesaria P, English D, Sakakeeny M, Rubin J, Pierce J, Shadduck R, FitzGerald T J
Abstract excerpt
Gamma-irradiation of plateau phase cultures of the clonal murine bone marrow stromal cell line D2XRII followed by cocultivation of a clonal interleukin 3 (IL-3) (granulocyte-macrophage colony-stimulating factor (GM-CSF)-dependent hematopoietic progenitor cell line FDC-P1JL26 results in a significant increase in "cobblestone islands" of attachment and emergence of subclonal factor-independent malignant sublines....
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