Article
Multilineage phenotypes of interleukin-3-dependent progenitor cells.
Blood - 15 Apr 1992
Ford A M, Healy L E, Bennett C A, Navarro E, Spooncer E, Greaves M F
Abstract excerpt
Interleukin-3 (IL-3)-dependent murine FDCP-mix cells have multilineage differentiation capacity; they are nonleukemic, have a normal karyotype, and are nonimmortalized. These cells coexpress on their cell surface the "early" B-lineage marker B220/CD45R and the myeloid marker Mac-1/iC3b receptor (CR3), transcribe germline T-cell receptor gamma genes, and express the macrophage lineage growth factor receptor gene...
Topics
- Animals
- Bone Marrow Cells
- Cell Differentiation
- Cell Line
- Genes, fms
- Genes, src
- Granulocyte Colony-Stimulating Factor
- Granulocyte-Macrophage Colony-Stimulating Factor
- Hematopoietic Stem Cells
- Interleukin-3
- Kinetics
