Article
Antisense modulation of the ICAM-1 phenotype of a model human bone marrow stromal cell line.
Experimental cell research - 10 Oct 1998
Weber M C, Groger R K, Tykocinski M L
Abstract excerpt
Efficient stable gene transfer was achieved in a model human bone marrow stromal cell line, KM-102, using both Epstein-Barr virus and BK virus episomal expression vectors. Using this episomal expression system, effective overexpression and inhibition of ICAM-1 expression was achieved in stably tr...
Topics
- BK Virus
- Bone Marrow Cells
- Cell Adhesion
- Cell Line
- Flow Cytometry
- Gene Transfer Techniques
- Genetic Vectors
- Hematopoietic Stem Cells
- Herpesvirus 4, Human
- Humans
- Intercellular Adhesion Molecule-1
- Leukemia
- Models, Biological
- Oligonucleotides, Antisense
- Phenotype
- Plasmids
- RNA, Antisense
- Stromal Cells