Article
Antisense modulation of the ICAM-1 phenotype of a model human bone marrow stromal cell line.
Experimental cell research - 10 Oct 1998
Weber M C, Groger R K, Tykocinski M L
Abstract excerpt
Efficient stable gene transfer was achieved in a model human bone marrow stromal cell line, KM-102, using both Epstein-Barr virus and BK virus episomal expression vectors. Using this episomal expression system, effective overexpression and inhibition of ICAM-1 expression was achieved in stably transfected KM-102 cells by sense and antisense RNA gene transfer, respectively. Loss of surface ICAM-1 on antisense...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
