Article
The effect of recombinant human interleukin-3 and recombinant human granulocyte-macrophage colony-stimulating factor on Fc gamma receptor expression and antibody-dependent cellular cytotoxicity of hematopoietic progenitor cells during in vitro myeloid maturation.
Experimental hematology - 1 Mar 1994
Ericson S G, Benoit N E, Mills L E, Fanger M W
Abstract excerpt
Enriched progenitor cell fractions from human bone marrow were induced to undergo myeloid maturation in culture using recombinant human interleukin-3 (rhIL-3) and granulocyte-macrophage colony stimulating factor (rhGM-CSF). A negative selection method using the murine monoclonal antibodies (MABs)...
Topics
- Antibodies, Monoclonal
- Antibody-Dependent Cell Cytotoxicity
- Antigens, CD
- Antigens, CD34
- Bone Marrow
- Bone Marrow Cells
- Cell Differentiation
- Cells, Cultured
- Flow Cytometry
- Granulocyte-Macrophage Colony-Stimulating Factor
- Hematopoiesis
- Hematopoietic Stem Cells