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Article

Differential regulation of primitive human hematopoietic cells in long- term cultures maintained on genetically engineered murine stromal cells

1 Aug 1991

Abstract excerpt

Various growth factors are known to stimulate both early and late stages of human hematopoietic cell development in semisolid assay systems, but their role as microenvironmental regulators is poorly understood. To address this problem, we developed a novel coculture system in which highly purified primitive human hematopoietic cells were seeded onto an irradiated feeder layer of cells from a murine marrow-derived...

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PMID: 1713512
DOI: 10.1182/blood.v78.3.666.666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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