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Article

HapBlock: haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms.

Bioinformatics (Oxford, England) - 1 Jan 2005

Zhang Kui, Qin Zhaohui, Chen Ting, Liu Jun S, Waterman Michael S, Sun Fengzhu

Abstract excerpt

UNLABELLED: Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed with regions of low LD. Such LD patterns make it possible to select a set of single nucleotide polymorphism (SNPs; tag SNPs) for genome-wide association studies. We have developed a suite of computer programs to analyze the block-like LD patterns and to select...

Topics

Algorithms
Chromosome Mapping
Expressed Sequence Tags
Genetic Variation
Haplotypes
Linkage Disequilibrium
Polymorphism, Single Nucleotide
Sequence Analysis, DNA
Software

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Identifiers

PMID: 15333454
DOI: 10.1093/bioinformatics/bth482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15333454-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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