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Article

Global haplotype partitioning for maximal associated SNP pairs.

BMC bioinformatics - 27 Aug 2009

Katanforoush Ali, Sadeghi Mehdi, Pezeshk Hamid, Elahi Elahe

Abstract excerpt

BACKGROUND: Global partitioning based on pairwise associations of SNPs has not previously been used to define haplotype blocks within genomes. Here, we define an association index based on LD between SNP pairs. We use the Fisher's exact test to assess the statistical significance of the LD estimator. By this test, each SNP pair is characterized as associated, independent, or not-statistically-significant. We set...

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Identifiers

PMID: 19712447
DOI: 10.1186/1471-2105-10-269
PMCID: PMC2749056

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