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Article

Haplotype block partitioning as a tool for dimensionality reduction in SNP association studies.

BMC genomics - 29 Aug 2008

Pattaro Cristian, Ruczinski Ingo, Fallin Danièle M, Parmigiani Giovanni

Abstract excerpt

BACKGROUND: Identification of disease-related genes in association studies is challenged by the large number of SNPs typed. To address the dilution of power caused by high dimensionality, and to generate results that are biologically interpretable, it is critical to take into consideration spatial correlation of SNPs along the genome. With the goal of identifying true genetic associations, partitioning the genome...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18759977
DOI: 10.1186/1471-2164-9-405
PMCID: PMC2547855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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