Haplotype block definition and its application.

doi:10.1142/9789812704856_0015

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Article

Haplotype block definition and its application.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2004

Zhu X, Zhang S, Kan D, Cooper R

Abstract excerpt

We present a simple two-stage procedure to define haplotype blocks and construct a statistic to test whether a polymorphism belongs to a block. Applying this method to the data of Gabriel et al. [2002] yielded longer haplotype blocks than were originally reported with a similar average percentage...

Topics

Algorithms
Computational Biology
Ethnicity
Haplotypes
Humans
Linkage Disequilibrium
Models, Genetic
Models, Statistical
Polymorphism, Single Nucleotide

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