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The Contribution of Genetic and Epigenetic Changes in Granulosa Cell Tumors of Ovarian Origin

15 Aug 2004

Abstract excerpt

PURPOSE: Granulosa cell tumors (GCTs) are relatively rare and are subtypes of the sex-cord stromal neoplasms. A better understanding of the molecular genetics underlying various steps in malignant transformation is critical to success in the battle against this disease. Changes in the status of methylation, known as epigenetic alterations, are one of the most common molecular alterations in human cancers,...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Ovarian cancer diagnosis and treatment
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15328194
DOI: 10.1158/1078-0432.ccr-04-0228

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