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Ovarian Adult Granulosa Cell Tumors: A Scoping Review of DNA Alterations and Their Known Significance.

Anticancer research - 1 Jan 2025

Karstensen Sven, Kaiser Karsten, Poulsen Tim Svenstrup, Jochumsen Kirsten, Høgdall Claus, Marcussen Niels, Lauzsus Finn Friis, Høgdall Estrid

Abstract excerpt

BACKGROUND/AIM: Adult granulosa cell tumor (aGCT) is a rare and challenging ovarian tumor due to its unpredictable recurrence and its associated increased risk of breast and endometrial cancer. Identifying and describing molecular alterations in tumors has become common with the advent of high-throughput sequencing. However, DNA sequencing in rare tumors, such as aGCT, often lacks statistical power due to the...

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PMID: 39740818
DOI: 10.21873/anticanres.17388

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