Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FOXL2 Mutation Status in Sex Cord-stromal Tumors Cannot be Predicted by Morphology.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2024

Wessman Sandra, Fuentes Beatriz Bohorquez, Severin-Karlsson Josefin, Westbom-Fremer Sofia, Nistér Monica, Kokaraki Georgia, Petta Tirzah Braz, Haglund Felix, Carlson Joseph W

Abstract excerpt

Granulosa-cell tumors (GCTs) are the most common type of malignant ovarian sex cord-stromal tumor (SCST). The histopathologic diagnosis of these tumors can be challenging. A recurrent somatic mutation of the forkhead box L2 (FOXL2) gene has been identified in adult GCT. In this retrospective single-center study of 44 SCST, a morphologic review together with analysis of FOXL2 C134W was evaluated in relation to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Forkhead Box Protein L2
Share to Forkhead Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Granulosa Cell Tumor

Share to Mutation

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 37255476
DOI: 10.1097/PGP.0000000000000953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FOXL2 Mutation Status in Sex Cord-stromal Tumors Cannot be Predicted by Morphology.PMID 37255476Read ↗

Ovarian Sex Cord-Stromal Neoplasms: An Overview of Molecular Events and How to Correlate Morphology With Molecular FindingsSemantic proximity Read ↗

Malignant Sex Cord-Stromal Tumor, Not Otherwise Specified, Harboring FOXL2, p53, and TERT Promoter Mutations: Report of a Case.Semantic proximity Read ↗

Evaluation of molecular analysis in challenging ovarian sex cord-stromal tumours: a review of 50 cases.Semantic proximity Read ↗

FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors: Genotype-Phenotype Correlation With Diagnostic Considerations.Semantic proximity Read ↗

Novel FOXL2 Mutation in an Ovarian Adult Granulosa Cell Tumor: Report of a Case With Diagnostic and Clinicopathologic Implications.Semantic proximity Read ↗

Mutation of FOXL2 in granulosa-cell tumors of the ovary.Semantic proximity Read ↗

Molecular assessment of testicular adult granulosa cell tumor demonstrates significant differences when compared to ovarian counterparts.Semantic proximity Read ↗

The C134W (402 C>G) FOXL2 mutation is absent in ovarian gynandroblastoma: insights into the genesis of an unusual tumour.Semantic proximity Read ↗

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature.Semantic proximity Read ↗

FOXL2 mutation is absent in uterine tumors resembling ovarian sex cord tumors.Semantic proximity Read ↗

Ovarian Adult Granulosa Cell Tumors: A Scoping Review of DNA Alterations and Their Known Significance.Semantic proximity Read ↗

A current perspective on the pathological assessment of <i><scp>FOXL</scp>2</i> in adult‐type granulosa cell tumours of the ovarySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.