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Article

PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor.

Journal of ovarian research - 27 Mar 2017

Wang Wen-Chung, Lee Ya-Ting, Lai Yen-Chein

Abstract excerpt

BACKGROUND: Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the FOXL2 402C > G mutation in adult granulosa cell tumor. Our previous case report showed that unique FOXL2 402C > G mutation and defective DNA mismatch repair...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28347324
DOI: 10.1186/s13048-017-0317-4
PMCID: PMC5369012

Genes

PMS2
FOXL2
MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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