Article
Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation.
Journal of ovarian research - 6 Sept 2014
Wang Wen-Chung, Lai Yen-Chein
Abstract excerpt
Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable late recurrent and malignant behavior. Recent molecular studies have characterized the FOXL2 402C > G mutation in adult-type granulosa cell tumor. In this study, we report an 80-year-old woman with a granulosa cell tumor arising from ovary. She presented with a huge pelvic mass with postmenopausal bleeding. No obvious...
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