Article
Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: implications for association analyses.
Human heredity - 1 Jan 2004
Chen Xiao-he, Rodríguez Santiago, Hawe Emma, Talmud Philippa J, Miller George J, Underhill Peter, Humphries Stephen E, Day Ian N M
Abstract excerpt
OBJECTIVE: Cohort and case-control genetic association studies offer the greatest power to detect small genotypic influences on disease phenotypes, relative to family-based designs. However, genetic subdivisions could confound studies involving unrelated individuals, but the topic has been little investigated. We examined geographical and interallelic association of SNP and microsatellite haplotypes of the Y...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
