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Article

Similarity by state/descent and genetic vector spaces: analysis of a longitudinal family study.

BMC genetics - 31 Dec 2003

Stassen Hans H, Hoffman Katrin, Scharfetter Christian

Abstract excerpt

Using the genome-wide screening data of the Framingham Heart Study (394 nuclear families, 1328 genotyped subjects, 397 marker loci) we have quantified the underlying genetic diversity through high-dimensional genetic feature vectors and constructed a genetic vector space for the analysis of population substructure. Adaptive clustering procedures led to three major subgroups that were regarded as being related to...

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Identifiers

PMID: 14975127
DOI: 10.1186/1471-2156-4-S1-S59
PMCID: PMC1866496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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