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Article

The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability.

Journal of molecular medicine (Berlin, Germany) - 1 Jul 2006

Brown C M, Rea T J, Hamon S C, Hixson J E, Boerwinkle E, Clark A G, Sing C F

Abstract excerpt

Apolipoproteins (apo) A-I and C-III are components of high-density lipoprotein-cholesterol (HDL-C), a quantitative trait negatively correlated with risk of cardiovascular disease (CVD). We analyzed the contribution of individual and pairwise combinations of single nucleotide polymorphisms (SNPs) in the APOA1/APOC3 genes to HDL-C variability to evaluate (1) consistency of published single-SNP studies with our...

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Source

Open in PubMed Open full text

Identifiers

PMID: 16705465
DOI: 10.1007/s00109-005-0037-x
PMCID: PMC1698872

Genes

APOA1
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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