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Article

Characterization of X-linked SNP genotypic variation in globally distributed human populations.

Genome biology - 28 Jan 2010

Casto Amanda M, Li Jun Z, Absher Devin, Myers Richard, Ramachandran Sohini, Feldman Marcus W

Abstract excerpt

BACKGROUND: The transmission pattern of the human X chromosome reduces its population size relative to the autosomes, subjects it to disproportionate influence by female demography, and leaves X-linked mutations exposed to selection in males. As a result, the analysis of X-linked genomic variation can provide insights into the influence of demography and selection on the human genome. Here we characterize the...

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Identifiers

PMID: 20109212
DOI: 10.1186/gb-2010-11-1-r10
PMCID: PMC2847713

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