Article
Genetic architecture and evolution of the lipoprotein(a) trait.
Current opinion in lipidology - 1 Apr 1999
Utermann G
Abstract excerpt
Apolipoprotein(a) is coded by one of the most polymorphic genes known in humans. In white and Asian populations variation in this gene is the major determinant of the plasma concentrations of the atherogenic lipoprotein(a) which varies enormously between individuals and considerably across populations. Recent studies have shown that the genetic architecture of the quantitative Lp(a) trait differs among major...
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