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Article

Limited Effect of Y Chromosome Variation on Coronary Artery Disease and Mortality in UK Biobank-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2022

Timmers Paul R H J, Wilson James F

Abstract excerpt

BACKGROUND: The effect of genetic variation in the male-specific region of the Y chromosome (MSY) on coronary artery disease and cardiovascular risk factors has been disputed. In this study, we systematically assessed the association of MSY genetic variation on these traits using a kin-cohort analysis of family disease history in the largest sample to date. METHODS: We tested 90 MSY haplogroups against coronary...

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Identifiers

PMID: 35861954
DOI: 10.1161/ATVBAHA.122.317664
PMCID: PMC9394501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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