Article
People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population.
European journal of human genetics : EJHG - 1 Feb 2012
Winney Bruce, Boumertit Abdelhamid, Day Tammy, Davison Dan, Echeta Chikodi, Evseeva Irina, Hutnik Katarzyna, Leslie Stephen, Nicodemus Kristin, Royrvik Ellen C, Tonks Susan, Yang Xiaofeng, Cheshire James, Longley Paul, Mateos Pablo, Groom Alexandra, Relton Caroline, Bishop D Tim, Black Kathryn, Northwood Emma, Parkinson Louise, Frayling Timothy M, Steele Anna, Sampson Julian R, King Turi, Dixon Ron, Middleton Derek, Jennings Barbara, Bowden Rory, Donnelly Peter, Bodmer Walter
Abstract excerpt
There is a great deal of interest in a fine-scale population structure in the UK, both as a signature of historical immigration events and because of the effect population structure may have on disease association studies. Although population structure appears to have a minor impact on the current generation of genome-wide association studies, it is likely to have a significant part in the next generation of...
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