Article
Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.
Matrix biology : journal of the International Society for Matrix Biology - 1 Jun 2004
Mátés Lajos, Nicolae Claudia, Mörgelin Matthias, Deák Ferenc, Kiss Ibolya, Aszódi Attila
Abstract excerpt
Matrilins are putative adaptor proteins of the extracellular matrix (ECM) which can form both collagen-dependent and collagen-independent filamentous networks. While all known matrilins (matrilin-1, -2, -3, and -4) are expressed in cartilage, only matrilin-2 and matrilin-4 are abundant in non-skeletal tissues. To clarify the biological role of matrilin-2, we have developed a matrilin-2-deficient mouse strain....
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