Article
Matrilin-3 Is Dispensable for Mouse Skeletal Growth and Development
29 Jan 2004
Abstract excerpt
Matrilin-3 belongs to the matrilin family of extracellular matrix (ECM) proteins and is primarily expressed in cartilage. Mutations in the gene encoding human matrilin-3 (MATN-3) lead to autosomal dominant skeletal disorders, such as multiple epiphyseal dysplasia (MED), which is characterized by short stature and early-onset osteoarthritis, and bilateral hereditary microepiphyseal dysplasia, a variant form of MED...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
