Article
Mammalian skeletogenesis and extracellular matrix: what can we learn from knockout mice?
Cell structure and function - 1 Apr 2000
Aszódi A, Bateman J F, Gustafsson E, Boot-Handford R, Fässler R
Abstract excerpt
Formation of the vertebrate skeleton and the proper functions of bony and cartilaginous elements are determined by extracellular, cell surface and intracellular molecules. Genetic and biochemical analyses of human heritable skeletal disorders as well as the generation of knockout mice provide useful tools to identify the key players of mammalian skeletogenesis. This review summarises our recent work with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
