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Article

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

The Journal of biological chemistry - 22 Dec 2006

Böse Kerstin, Nischt Roswitha, Page Anton, Bader Bernhard L, Paulsson Mats, Smyth Neil

Abstract excerpt

Nidogens are two ubiquitous basement membrane proteins produced mainly by mesenchymal cells. Nidogen-mediated interactions, in particular with laminin, collagen IV, and perlecan have been considered important in the formation and maintenance of the basement membrane. However, whereas mice lacking both nidogen isoforms or carrying mutations in the high affinity nidogen-binding site upon the laminin gamma1 chain...

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Identifiers

PMID: 17023412
DOI: 10.1074/jbc.M607886200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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