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Article

Biogenesis and function of fibrillin assemblies.

Cell and tissue research - 1 Jan 2010

Ramirez Francesco, Sakai Lynn Y

Abstract excerpt

Fibrillin-1 and fibrillin-2 are large cysteine-rich glycoproteins that serve two key physiological functions: as supporting structures that impart tissue integrity and as regulators of signaling events that instruct cell performance. The structural role of fibrillins is exerted through the temporal and hierarchical assembly of microfibrils and elastic fibers, whereas the instructive role reflects the ability of...

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Identifiers

PMID: 19513754
DOI: 10.1007/s00441-009-0822-x
PMCID: PMC2819175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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